| From | Team | Fee | Apps | Goals | To | |
|---|---|---|---|---|---|---|
| 2005 | Nacional (Uru) | - | 27 | 10 | 2006 | (Player) |
| 2005 | FC Groningen | - | 27 | 10 | 2006 | (Player) |
| 2006 | FC Groningen | - | 29 | 10 | 2007 | (Player) |
| 2007 | Ajax | £7,000,000 | 110 | 81 | 2011 | (Player) |
| 2011 | Liverpool | £22,800,000 | 110 | 69 | 2014 | (Player) |
| 2014 | Barcelona | £75,000,000 | 191 | 147 | 2020 | (Player) |
| 2020 | Atlético Madrid | Free | 67 | 32 | 2022 | (Player) |
| 2022 | Nacional (Uru) | Free | 14 | 8 | 2023 | (Player) |
| 2023 | Gremio | Free | 33 | 17 | 2023 | (Player) |
| 2023 | Inter Miami | - | 55 | 30 | Current | (Player) |